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Synthesis of (R)-mandelic acid and (R)-mandelic acid amide by recombinant E. coli strains expressing a (R)-specific oxynitrilase and an arylacetonitrilase
ABSTRACT: OBJECTIVES: Chiral 2-hydroxycarboxylic acids and 2-hydroxycarboxamides are valuable synthons for the chemical industry. RESULTS: The biocatalytic syntheses of (R)-mandelic acid and (R)-mandelic acid amide by recombinant Escherichia coli clones were studied. Strains were constructed which s...
Autores principales: | Müller, Erik, Sosedov, Olga, Gröning, Janosch Alexander David, Stolz, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796878/ https://www.ncbi.nlm.nih.gov/pubmed/32936375 http://dx.doi.org/10.1007/s10529-020-02998-8 |
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