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Predicting development of ipilimumab-induced hypophysitis: utility of T4 and TSH index but not TSH
PURPOSE: Ipilimumab, a monoclonal antibody inhibiting CLTA-4, is an established treatment in metastatic melanoma, either alone or in combination with nivolumab, and results in immune mediated adverse events, including endocrinopathy. Hypophysitis is one of the most common endocrine abnormalities. An...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796881/ https://www.ncbi.nlm.nih.gov/pubmed/32449093 http://dx.doi.org/10.1007/s40618-020-01297-3 |