Genetic screening for single-cell variability modulators driving therapy resistance

Cellular plasticity describes cells’ ability to transition from one set of phenotypes to another. In melanoma, transient fluctuations in the molecular state of tumor cells mark the formation of rare cells primed to survive BRAF inhibition and reprogram into a stably drug resistant fate. However, the...

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Detalles Bibliográficos
Autores principales: Torre, Eduardo A., Arai, Eri, Bayatpour, Sareh, Jiang, Connie L., Beck, Lauren E., Emert, Benjamin L., Shaffer, Sydney M., Mellis, Ian A., Fane, Mitchell E., Alicea, Gretchen M., Budinich, Krista A., Weeraratna, Ashani T., Shi, Junwei, Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796998/
https://www.ncbi.nlm.nih.gov/pubmed/33398196
http://dx.doi.org/10.1038/s41588-020-00749-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796998/
https://www.ncbi.nlm.nih.gov/pubmed/33398196
http://dx.doi.org/10.1038/s41588-020-00749-z

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