Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene

The mammalian Ate1 gene encodes an arginyl transferase enzyme with tumor suppressor function that depends on the inclusion of one of the two mutually exclusive exons (MXE), exons 7a and 7b. We report that the molecular mechanism underlying MXE splicing in Ate1 involves five conserved regulatory intr...

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Detalles Bibliográficos
Autores principales: Kalinina, Marina, Skvortsov, Dmitry, Kalmykova, Svetlana, Ivanov, Timofei, Dontsova, Olga, Pervouchine, Dmitri D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797038/
https://www.ncbi.nlm.nih.gov/pubmed/33330934
http://dx.doi.org/10.1093/nar/gkaa1208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797038/
https://www.ncbi.nlm.nih.gov/pubmed/33330934
http://dx.doi.org/10.1093/nar/gkaa1208

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