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The nature of the modification at position 37 of tRNA(Phe) correlates with acquired taxol resistance

Acquired drug resistance is a major obstacle in cancer therapy. Recent studies revealed that reprogramming of tRNA modifications modulates cancer survival in response to chemotherapy. However, dynamic changes in tRNA modification were not elucidated. In this study, comparative analysis of the human...

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Detalles Bibliográficos
Autores principales: Pan, Yu, Yan, Tong-Meng, Wang, Jing-Rong, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797046/
https://www.ncbi.nlm.nih.gov/pubmed/33290562
http://dx.doi.org/10.1093/nar/gkaa1164