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A simplified strategy for titrating gene expression reveals new relationships between genotype, environment, and bacterial growth

A lack of high-throughput techniques for making titrated, gene-specific changes in expression limits our understanding of the relationship between gene expression and cell phenotype. Here, we present a generalizable approach for quantifying growth rate as a function of titrated changes in gene expre...

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Detalles Bibliográficos
Autores principales: Mathis, Andrew D, Otto, Ryan M, Reynolds, Kimberly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797047/
https://www.ncbi.nlm.nih.gov/pubmed/33221881
http://dx.doi.org/10.1093/nar/gkaa1073