Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14

CRISPR–Cas systems are adaptive immune systems in bacteria and archaea to defend against mobile genetic elements (MGEs) and have been repurposed as genome editing tools. Anti-CRISPR (Acr) proteins are produced by MGEs to counteract CRISPR–Cas systems and can be used to regulate genome editing by CRI...

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Detalles Bibliográficos
Autores principales: Gabel, Clinton, Li, Zhuang, Zhang, Heng, Chang, Leifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797054/
https://www.ncbi.nlm.nih.gov/pubmed/33332569
http://dx.doi.org/10.1093/nar/gkaa1199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797054/
https://www.ncbi.nlm.nih.gov/pubmed/33332569
http://dx.doi.org/10.1093/nar/gkaa1199

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