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Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing

Chromatin properties are regulated by complex networks of epigenome modifications. Currently, it is unclear how these modifications interact and if they control downstream effects such as gene expression. We employed promiscuous chromatin binding of a zinc finger fused catalytic domain of DNMT3A to...

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Detalles Bibliográficos
Autores principales: Broche, Julian, Kungulovski, Goran, Bashtrykov, Pavel, Rathert, Philipp, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797067/
https://www.ncbi.nlm.nih.gov/pubmed/33300025
http://dx.doi.org/10.1093/nar/gkaa1169