The fragility of a structurally diverse duplication block triggers recurrent genomic amplification

The human genome contains hundreds of large, structurally diverse blocks that are insufficiently represented in the reference genome and are thus not amenable to genomic analyses. Structural diversity in the human population suggests that these blocks are unstable in the germline; however, whether o...

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Detalles Bibliográficos
Autores principales: Suzuki, Ryusuke, Murata, Michael M, Manguso, Nicholas, Watanabe, Takaaki, Mouakkad-Montoya, Lila, Igari, Fumie, Rahman, Md Maminur, Qu, Ying, Cui, Xiaojiang, Giuliano, Armando E, Takeda, Shunichi, Tanaka, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797068/
https://www.ncbi.nlm.nih.gov/pubmed/33290559
http://dx.doi.org/10.1093/nar/gkaa1136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797068/
https://www.ncbi.nlm.nih.gov/pubmed/33290559
http://dx.doi.org/10.1093/nar/gkaa1136

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