Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin

Human genome stability requires efficient repair of oxidized bases, which is initiated via damage recognition and excision by NEIL1 and other base excision repair (BER) pathway DNA glycosylases (DGs). However, the biological mechanisms underlying detection of damaged bases among the million-fold exc...

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Detalles Bibliográficos
Autores principales: Bacolla, Albino, Sengupta, Shiladitya, Ye, Zu, Yang, Chunying, Mitra, Joy, De-Paula, Ruth B, Hegde, Muralidhar L, Ahmed, Zamal, Mort, Matthew, Cooper, David N, Mitra, Sankar, Tainer, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797072/
https://www.ncbi.nlm.nih.gov/pubmed/33300026
http://dx.doi.org/10.1093/nar/gkaa1120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797072/
https://www.ncbi.nlm.nih.gov/pubmed/33300026
http://dx.doi.org/10.1093/nar/gkaa1120

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