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Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Human genome stability requires efficient repair of oxidized bases, which is initiated via damage recognition and excision by NEIL1 and other base excision repair (BER) pathway DNA glycosylases (DGs). However, the biological mechanisms underlying detection of damaged bases among the million-fold exc...
Autores principales: | Bacolla, Albino, Sengupta, Shiladitya, Ye, Zu, Yang, Chunying, Mitra, Joy, De-Paula, Ruth B, Hegde, Muralidhar L, Ahmed, Zamal, Mort, Matthew, Cooper, David N, Mitra, Sankar, Tainer, John A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797072/ https://www.ncbi.nlm.nih.gov/pubmed/33300026 http://dx.doi.org/10.1093/nar/gkaa1120 |
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