Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification

The roles of ISL1 and LHX3 in the development of spinal motor neurons have been well established. Whereas LHX3 triggers differentiation into interneurons, the additional expression of ISL1 in developing neuronal cells is sufficient to redirect their developmental trajectory towards spinal motor neur...

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Detalles Bibliográficos
Autores principales: Smith, Ngaio C., Wilkinson-White, Lorna E., Kwan, Ann H.Y., Trewhella, Jill, Matthews, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797366/
https://www.ncbi.nlm.nih.gov/pubmed/33458649
http://dx.doi.org/10.1016/j.yjsbx.2020.100043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797366/
https://www.ncbi.nlm.nih.gov/pubmed/33458649
http://dx.doi.org/10.1016/j.yjsbx.2020.100043

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