Construction and application of a human scFv phage display library based on Cre-LoxP recombination for anti-PCSK9 antibody selection

A large human natural single-chain fragment variable (scFv) phage library was constructed based on Cre-LoxP recombination, and used to successfully identify antibodies against proprotein convertase subtilisin/kexin type 9 (PCSK9). The library was derived from 400 blood samples, 30 bone marrow sample...

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Detalles Bibliográficos
Autores principales: Dong, Yuan, Meng, Fanwei, Wang, Zhiheng, Yu, Tianyi, Chen, An, Xu, Song, Wang, Jianming, Yin, Moli, Tang, Lu, Hu, Chuanmin, Wang, Huiyan, Cai, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797424/
https://www.ncbi.nlm.nih.gov/pubmed/33416098
http://dx.doi.org/10.3892/ijmm.2020.4822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797424/
https://www.ncbi.nlm.nih.gov/pubmed/33416098
http://dx.doi.org/10.3892/ijmm.2020.4822

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