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Regulatory role of DEPTOR-mediated cellular autophagy and mitochondrial reactive oxygen species in angiogenesis in multiple myeloma

DEPTOR, an inhibitor of mammalian target of rapamycin (mTOR), is essential for the survival of multiple myeloma (MM) cells. The expression level of DEPTOR is closely related to the prognosis of patients with MM treated with the antiangiogenic agent thalidomide; however, its role in the regulation of...

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Detalles Bibliográficos
Autores principales: Wang, Jizhen, Chen, Junmin, Qiu, Dongbiao, Zeng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797453/
https://www.ncbi.nlm.nih.gov/pubmed/33416146
http://dx.doi.org/10.3892/ijmm.2020.4831