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Regulatory role of DEPTOR-mediated cellular autophagy and mitochondrial reactive oxygen species in angiogenesis in multiple myeloma
DEPTOR, an inhibitor of mammalian target of rapamycin (mTOR), is essential for the survival of multiple myeloma (MM) cells. The expression level of DEPTOR is closely related to the prognosis of patients with MM treated with the antiangiogenic agent thalidomide; however, its role in the regulation of...
Autores principales: | Wang, Jizhen, Chen, Junmin, Qiu, Dongbiao, Zeng, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797453/ https://www.ncbi.nlm.nih.gov/pubmed/33416146 http://dx.doi.org/10.3892/ijmm.2020.4831 |
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