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Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds

As a promising target for alternative antimicrobials, bacterial recombinase A (RecA) protein has attracted much attention for its roles in antibiotic-driven SOS response and mutagenesis. Naphthalene polysulfonated compounds (NPS) such as suramin have previously been explored as antibiotic adjuvants...

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Detalles Bibliográficos
Autores principales: Zhou, Ziyuan, Pan, Qing, Lv, Xinchen, Yuan, Jing, Zhang, Yang, Zhang, Ming-Xia, Ke, Ming, Mo, Xiao-Mei, Xie, Yong-Li, Liu, Yingxia, Chen, Ting, Liang, Mingchan, Yin, Feng, Liu, Lei, Zhou, Yiqing, Qiao, Kun, Liu, Rui, Li, Zigang, Wong, Nai-Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797525/
https://www.ncbi.nlm.nih.gov/pubmed/33458611
http://dx.doi.org/10.1016/j.isci.2020.101952