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A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment

Multigram drug depot systems for extended drug release could transform our capacity to effectively treat patients across a myriad of diseases. For example, tuberculosis (TB) requires multimonth courses of daily multigram doses for treatment. To address the challenge of prolonged dosing for regimens...

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Detalles Bibliográficos
Autores principales: Verma, Malvika, Vishwanath, Karan, Eweje, Feyisope, Roxhed, Niclas, Grant, Tyler, Castaneda, Macy, Steiger, Christoph, Mazdiyasni, Hormoz, Bensel, Taylor, Minahan, Daniel, Soares, Vance, Salama, John A. F., Lopes, Aaron, Hess, Kaitlyn, Cleveland, Cody, Fulop, Daniel J., Hayward, Alison, Collins, Joy, Tamang, Siddartha M., Hua, Tiffany, Ikeanyi, Chinonyelum, Zeidman, Gal, Mule, Elizabeth, Boominathan, Sooraj, Popova, Ellena, Miller, Jonathan B., Bellinger, Andrew M., Collins, David, Leibowitz, Dalia, Batra, Shelly, Ahuja, Sandeep, Bajiya, Manju, Batra, Sonali, Sarin, Rohit, Agarwal, Upasna, Khaparde, Sunil D., Gupta, Neeraj K., Gupta, Deepak, Bhatnagar, Anuj K., Chopra, Kamal K., Sharma, Nandini, Khanna, Ashwani, Chowdhury, Jayeeta, Stoner, Robert, Slocum, Alexander H., Cima, Michael J., Furin, Jennifer, Langer, Robert, Traverso, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797620/
https://www.ncbi.nlm.nih.gov/pubmed/30867322
http://dx.doi.org/10.1126/scitranslmed.aau6267