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Chimeric antigen receptor T-cell immunotherapy in breast cancer: development and challenges

Chimeric antigen receptor (CAR) T-cell therapy is an innovative form of immunotherapy wherein autologous T-cells are genetically modified to express chimeric receptors encoding an antigen-specific single-chain variable fragment and costimulatory molecules. Moreover, CAR T-cell therapy can only work...

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Detalles Bibliográficos
Autores principales: Toulouie, Sara, Johanning, Gary, Shi, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797648/
https://www.ncbi.nlm.nih.gov/pubmed/33442419
http://dx.doi.org/10.7150/jca.54095