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Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy

Alzheimer's disease (AD) is currently ranked as the third leading cause of death for eldly people, just behind heart disease and cancer. Autophagy is declined with aging. Our study determined the biphasic changes of miR-331-3p and miR-9-5p associated with AD progression in APPswe/PS1dE9 mouse m...

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Detalles Bibliográficos
Autores principales: Chen, Meng-Lu, Hong, Chun-Gu, Yue, Tao, Li, Hong-Ming, Duan, Ran, Hu, Wen-Bao, Cao, Jia, Wang, Zhen-Xing, Chen, Chun-Yuan, Hu, Xiong-Ke, Wu, Ben, Liu, Hao-Ming, Tan, Yi-Juan, Liu, Jiang-Hua, Luo, Zhong-Wei, Zhang, Yan, Rao, Shan-Shan, Luo, Ming-Jie, Yin, Hao, Wang, Yi-Yi, Xia, Kun, Tang, Si-Yuan, Xie, Hui, Liu, Zheng-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797673/
https://www.ncbi.nlm.nih.gov/pubmed/33500732
http://dx.doi.org/10.7150/thno.47408