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Co-delivery of 5-fluorouracil and miRNA-34a mimics by host-guest self-assembly nanocarriers for efficacious targeted therapy in colorectal cancer patient-derived tumor xenografts

Rationale: A co-delivery system that can transport chemotherapeutic drugs and nucleotide drugs to distinct targets in tumors is an attractive strategy for cancer therapy. In this study, well-defined targeted quantum dot (QD)-based multifunctional nanocarriers were developed through self-assembly dri...

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Detalles Bibliográficos
Autores principales: Xu, Jianbin, Zhang, Guolin, Luo, Xin, Wang, Di, Zhou, Wei, Zhang, Yan, Zhang, Wei, Chen, Jiaxin, Meng, Qing, Chen, Engeng, Chen, Heng, Song, Zhangfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797688/
https://www.ncbi.nlm.nih.gov/pubmed/33500737
http://dx.doi.org/10.7150/thno.52076