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Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF‐β—Smad2/3 signaling and Wnt signaling in Neovascular Age‐Related Macular Degeneration

Subretinal fibrosis is a common pathological change that causes vision loss in neovascular age-related macular degeneration (nAMD). Treatment modalities for subretinal fibrosis are limited. In the present study, the effects of fenofibrate, a specific peroxisome proliferator–activated receptor alpha...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Jiang, Nan, Zhang, Yuhan, Ye, Sihao, Liang, Xu, Wang, Xin, Lin, Xiang, Zong, Rongrong, Chen, Haoyu, Liu, Zuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797782/
https://www.ncbi.nlm.nih.gov/pubmed/33442383
http://dx.doi.org/10.3389/fphar.2020.580884