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Proteomic and functional mapping of cardiac Na(V)1.5 channel phosphorylation sites
Phosphorylation of the voltage-gated Na(+) (Na(V)) channel Na(V)1.5 regulates cardiac excitability, yet the phosphorylation sites regulating its function and the underlying mechanisms remain largely unknown. Using a systematic, quantitative phosphoproteomic approach, we analyzed Na(V)1.5 channel com...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797897/ https://www.ncbi.nlm.nih.gov/pubmed/33410863 http://dx.doi.org/10.1085/jgp.202012646 |