Proteomic and functional mapping of cardiac Na(V)1.5 channel phosphorylation sites

Phosphorylation of the voltage-gated Na(+) (Na(V)) channel Na(V)1.5 regulates cardiac excitability, yet the phosphorylation sites regulating its function and the underlying mechanisms remain largely unknown. Using a systematic, quantitative phosphoproteomic approach, we analyzed Na(V)1.5 channel com...

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Detalles Bibliográficos
Autores principales: Lorenzini, Maxime, Burel, Sophie, Lesage, Adrien, Wagner, Emily, Charrière, Camille, Chevillard, Pierre-Marie, Evrard, Bérangère, Maloney, Dan, Ruff, Kiersten M., Pappu, Rohit V., Wagner, Stefan, Nerbonne, Jeanne M., Silva, Jonathan R., Townsend, R. Reid, Maier, Lars S., Marionneau, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797897/
https://www.ncbi.nlm.nih.gov/pubmed/33410863
http://dx.doi.org/10.1085/jgp.202012646

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