Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling

Receptor degradation terminates signaling by activated receptor tyrosine kinases. Degradation of EGFR occurs in lysosomes and requires the switching of RAB5 for RAB7 on late endosomes to enable their fusion with the lysosome, but what controls this critical switching is poorly understood. We show th...

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Detalles Bibliográficos
Autores principales: Lonic, Ana, Gehling, Freya, Belle, Leila, Li, Xiaochun, Schieber, Nicole L., Nguyen, Elizabeth V., Goodall, Gregory J., Parton, Robert G., Daly, Roger J., Khew-Goodall, Yeesim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797899/
https://www.ncbi.nlm.nih.gov/pubmed/33411917
http://dx.doi.org/10.1083/jcb.201902073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797899/
https://www.ncbi.nlm.nih.gov/pubmed/33411917
http://dx.doi.org/10.1083/jcb.201902073

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