Metagenomic discovery and functional validation of L-asparaginases with anti-leukemic effect from the Caspian Sea

By screening 27,000 publicly available prokaryotic genomes, we recovered ca. 6300 type I and ca. 5200 type II putative L-asparaginase highlighting the vast potential of prokaryotes. Caspian water with similar salt composition to the human serum was targeted for in silico L-asparaginase screening. We...

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Detalles Bibliográficos
Autores principales: Sobat, Motahareh, Asad, Sedigheh, Kabiri, Mahboubeh, Mehrshad, Maliheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797908/
https://www.ncbi.nlm.nih.gov/pubmed/33458619
http://dx.doi.org/10.1016/j.isci.2020.101973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797908/
https://www.ncbi.nlm.nih.gov/pubmed/33458619
http://dx.doi.org/10.1016/j.isci.2020.101973

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