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Metagenomic discovery and functional validation of L-asparaginases with anti-leukemic effect from the Caspian Sea

By screening 27,000 publicly available prokaryotic genomes, we recovered ca. 6300 type I and ca. 5200 type II putative L-asparaginase highlighting the vast potential of prokaryotes. Caspian water with similar salt composition to the human serum was targeted for in silico L-asparaginase screening. We...

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Detalles Bibliográficos
Autores principales:	Sobat, Motahareh, Asad, Sedigheh, Kabiri, Mahboubeh, Mehrshad, Maliheh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797908/ https://www.ncbi.nlm.nih.gov/pubmed/33458619 http://dx.doi.org/10.1016/j.isci.2020.101973

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