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Global mapping of translation initiation sites by TIS profiling in budding yeast

Translation initiation site (TIS) profiling allows for the genome-wide identification of TISs in vivo by exclusively capturing mRNA fragments within ribosomes that have just completed translation initiation. It leverages translation inhibitors, such as harringtonine and lactimidomycin (LTM), that pr...

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Detalles Bibliográficos
Autores principales: Hollerer, Ina, Powers, Emily N., Brar, Gloria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797918/
https://www.ncbi.nlm.nih.gov/pubmed/33458709
http://dx.doi.org/10.1016/j.xpro.2020.100250