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Vitamin D sufficiency enhances differentiation of patient-derived prostate epithelial organoids

Vitamin D is an essential steroid hormone that regulates systemic calcium homeostasis and cell fate decisions. The prostate gland is hormonally regulated, requiring steroids for proliferation and differentiation of secretory luminal cells. Vitamin D deficiency is associated with an increased risk of...

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Detalles Bibliográficos
Autores principales: McCray, Tara, Pacheco, Julian V., Loitz, Candice C., Garcia, Jason, Baumann, Bethany, Schlicht, Michael J., Valyi-Nagy, Klara, Abern, Michael R., Nonn, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797919/
https://www.ncbi.nlm.nih.gov/pubmed/33458620
http://dx.doi.org/10.1016/j.isci.2020.101974