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Vitamin D sufficiency enhances differentiation of patient-derived prostate epithelial organoids
Vitamin D is an essential steroid hormone that regulates systemic calcium homeostasis and cell fate decisions. The prostate gland is hormonally regulated, requiring steroids for proliferation and differentiation of secretory luminal cells. Vitamin D deficiency is associated with an increased risk of...
Autores principales: | McCray, Tara, Pacheco, Julian V., Loitz, Candice C., Garcia, Jason, Baumann, Bethany, Schlicht, Michael J., Valyi-Nagy, Klara, Abern, Michael R., Nonn, Larisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797919/ https://www.ncbi.nlm.nih.gov/pubmed/33458620 http://dx.doi.org/10.1016/j.isci.2020.101974 |
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