Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retention

BACKGROUND: Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased population of immunocompromised patients. Notable potential of the pulmonary route has been witnessed in antifungal delivery due to distinct advantages of direct lung targeting and first-pass evasion. The cur...

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Detalles Bibliográficos
Autores principales: Kaur, Ranjot, Dennison, Sarah R., Burrow, Andrea J., Rudramurthy, Shivaprakash M., Swami, Rajan, Gorki, Varun, Katare, O. P., Kaushik, Anupama, Singh, Bhupinder, Singh, Kamalinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798018/
https://www.ncbi.nlm.nih.gov/pubmed/33430888
http://dx.doi.org/10.1186/s12951-020-00731-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798018/
https://www.ncbi.nlm.nih.gov/pubmed/33430888
http://dx.doi.org/10.1186/s12951-020-00731-1

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