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Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retention
BACKGROUND: Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased population of immunocompromised patients. Notable potential of the pulmonary route has been witnessed in antifungal delivery due to distinct advantages of direct lung targeting and first-pass evasion. The cur...
Autores principales: | Kaur, Ranjot, Dennison, Sarah R., Burrow, Andrea J., Rudramurthy, Shivaprakash M., Swami, Rajan, Gorki, Varun, Katare, O. P., Kaushik, Anupama, Singh, Bhupinder, Singh, Kamalinder K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798018/ https://www.ncbi.nlm.nih.gov/pubmed/33430888 http://dx.doi.org/10.1186/s12951-020-00731-1 |
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