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MicroRNA-7 modulates cellular senescence to relieve gemcitabine resistance by targeting PARP1/NF-κB signaling in pancreatic cancer cells

Senescence is activated in response to gemcitabine to prevent the propagation of cancer cells. However, there is little evidence on whether senescence is involved in gemcitabine resistance in pancreatic cancer. Increasing evidence has demonstrated that microRNAs (miRs) are potential regulators of ce...

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Detalles Bibliográficos
Autores principales: Ye, Zhi-Qiang, Chen, Han-Bin, Zhang, Tai-Yu, Chen, Zhi, Tian, Ling, Gu, Dian-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798037/
https://www.ncbi.nlm.nih.gov/pubmed/33552258
http://dx.doi.org/10.3892/ol.2020.12400