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The role of microglia membrane potential in chemotaxis

Microglia react to danger signals by rapid and targeted extension of cellular processes towards the source of the signal. This positive chemotactic response is accompanied by a hyperpolarization of the microglia membrane. Here, we show that optogenetic depolarization of microglia has little effect o...

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Detalles Bibliográficos
Autores principales: Laprell, Laura, Schulze, Christian, Brehme, Marie-Luise, Oertner, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798195/
https://www.ncbi.nlm.nih.gov/pubmed/33423699
http://dx.doi.org/10.1186/s12974-020-02048-0