Protein over-expression in Escherichia coli triggers adaptation analogous to antimicrobial resistance

BACKGROUND: The E. coli pET system is the most widely used protein over-expression system worldwide. It relies on the assumption that all cells produce target protein and it is generally believed that integral membrane protein (IMP) over-expression is more toxic than their soluble counterparts. RESU...

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Detalles Bibliográficos
Autores principales: James, Jack, Yarnall, Benjamin, Koranteng, Andy, Gibson, Jane, Rahman, Tahmina, Doyle, Declan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798265/
https://www.ncbi.nlm.nih.gov/pubmed/33430875
http://dx.doi.org/10.1186/s12934-020-01462-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798265/
https://www.ncbi.nlm.nih.gov/pubmed/33430875
http://dx.doi.org/10.1186/s12934-020-01462-6

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