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JOINT for large-scale single-cell RNA-sequencing analysis via soft-clustering and parallel computing
BACKGROUND: Single-cell RNA-Sequencing (scRNA-Seq) has provided single-cell level insights into complex biological processes. However, the high frequency of gene expression detection failures in scRNA-Seq data make it challenging to achieve reliable identification of cell-types and Differentially Ex...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798298/ https://www.ncbi.nlm.nih.gov/pubmed/33430769 http://dx.doi.org/10.1186/s12864-020-07302-6 |