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Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity

BACKGROUND: Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first malaria vaccine Mosquirix™ and very promising data using cryopreserved P. fa...

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Detalles Bibliográficos
Autores principales: Seidel-Greven, Melanie, Addai-Mensah, Otchere, Spiegel, Holger, Chiegoua Dipah, Gwladys Nina, Schmitz, Stefan, Breuer, Gudrun, Frempong, Margaret, Reimann, Andreas, Klockenbring, Torsten, Fischer, Rainer, Barth, Stefan, Fendel, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798374/
https://www.ncbi.nlm.nih.gov/pubmed/33430886
http://dx.doi.org/10.1186/s12936-020-03548-3