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Casein‐enhanced uptake and disease‐modifying bioactivity of ingested extracellular vesicles

Extracellular vesicles (EVs) from cardiac stromal cells, developed as therapeutic candidates, improve dystrophic muscle function when administered parenterally, but oral delivery remains untested. We find that casein, the dominant protein in breast milk, enhances the uptake and bioactivity of ingest...

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Detalles Bibliográficos
Autores principales: Aminzadeh, Mark A., Fournier, Mario, Akhmerov, Akbarshakh, Jones‐Ungerleider, K. Candis, Valle, Jackelyn B., Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798403/
https://www.ncbi.nlm.nih.gov/pubmed/33456725
http://dx.doi.org/10.1002/jev2.12045