Weak acids as an alternative anti-microbial therapy

Weak acids such as acetic acid and N-acetyl cysteine (NAC) at pH less than their pKa can effectively eradicate biofilms due to their ability to penetrate the biofilm matrix and the cell membrane. However, the optimum conditions for their activity against drug resistant strains, and safety, need to b...

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Detalles Bibliográficos
Autores principales: Kundukad, Binu, Udayakumar, Gayathri, Grela, Erin, Kaur, Dhamanpreet, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798471/
https://www.ncbi.nlm.nih.gov/pubmed/33447805
http://dx.doi.org/10.1016/j.bioflm.2020.100019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798471/
https://www.ncbi.nlm.nih.gov/pubmed/33447805
http://dx.doi.org/10.1016/j.bioflm.2020.100019

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