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Weak acids as an alternative anti-microbial therapy
Weak acids such as acetic acid and N-acetyl cysteine (NAC) at pH less than their pKa can effectively eradicate biofilms due to their ability to penetrate the biofilm matrix and the cell membrane. However, the optimum conditions for their activity against drug resistant strains, and safety, need to b...
Autores principales: | Kundukad, Binu, Udayakumar, Gayathri, Grela, Erin, Kaur, Dhamanpreet, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798471/ https://www.ncbi.nlm.nih.gov/pubmed/33447805 http://dx.doi.org/10.1016/j.bioflm.2020.100019 |
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