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Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection

To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, a humanized decoy antibody (ACE2‐Fc fusion protein) was designed to target the interaction between viral spike protein and its cellular receptor, angiotensin‐converting enzyme 2 (...

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Detalles Bibliográficos
Autores principales: Huang, Kuo‐Yen, Lin, Ming‐Shiu, Kuo, Ting‐Chun, Chen, Ci‐Ling, Lin, Chung‐Chih, Chou, Yu‐Chi, Chao, Tai‐Ling, Pang, Yu‐Hao, Kao, Han‐Chieh, Huang, Rih‐Sheng, Lin, Steven, Chang, Sui‐Yuan, Yang, Pan‐Chyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799362/
https://www.ncbi.nlm.nih.gov/pubmed/33159417
http://dx.doi.org/10.15252/emmm.202012828