Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a multi‐system disease characterized primarily by progressive muscle weakness. Cognitive dysfunction is commonly observed in patients; however, factors influencing risk for cognitive dysfunction remain elusive. Using sparse canonical correlation analysis (sCCA)...

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Detalles Bibliográficos
Autores principales: Placek, Katerina, Benatar, Michael, Wuu, Joanne, Rampersaud, Evadnie, Hennessy, Laura, Van Deerlin, Vivianna M, Grossman, Murray, Irwin, David J, Elman, Lauren, McCluskey, Leo, Quinn, Colin, Granit, Volkan, Statland, Jeffrey M, Burns, Ted M, Ravits, John, Swenson, Andrea, Katz, Jon, Pioro, Erik P, Jackson, Carlayne, Caress, James, So, Yuen, Maiser, Samuel, Walk, David, Lee, Edward B, Trojanowski, John Q, Cook, Philip, Gee, James, Sha, Jin, Naj, Adam C, Rademakers, Rosa, Chen, Wenan, Wu, Gang, Paul Taylor, J, McMillan, Corey T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799365/
https://www.ncbi.nlm.nih.gov/pubmed/33270986
http://dx.doi.org/10.15252/emmm.202012595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799365/
https://www.ncbi.nlm.nih.gov/pubmed/33270986
http://dx.doi.org/10.15252/emmm.202012595

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