Platelets express adaptor proteins of the extrinsic apoptosis pathway and can activate caspase-8

BACKGROUND: Apoptotic pathways in platelets are important for their survival and function. Platelet apoptosis may be involved in the pathogenesis of immune thrombocytopenia (ITP), an autoimmune-mediated disease. In contrast to the intrinsic apoptosis pathway, not much is known about the extrinsic pa...

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Detalles Bibliográficos
Autores principales: Goelz, Nadine, Eekels, Julia J. M., Pantic, Milica, Kamber, Christoph T., Speer, Oliver, Franzoso, Francesca D., Schmugge, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799768/
https://www.ncbi.nlm.nih.gov/pubmed/33428668
http://dx.doi.org/10.1371/journal.pone.0244848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799768/
https://www.ncbi.nlm.nih.gov/pubmed/33428668
http://dx.doi.org/10.1371/journal.pone.0244848

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