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Platelets express adaptor proteins of the extrinsic apoptosis pathway and can activate caspase-8
BACKGROUND: Apoptotic pathways in platelets are important for their survival and function. Platelet apoptosis may be involved in the pathogenesis of immune thrombocytopenia (ITP), an autoimmune-mediated disease. In contrast to the intrinsic apoptosis pathway, not much is known about the extrinsic pa...
Autores principales: | Goelz, Nadine, Eekels, Julia J. M., Pantic, Milica, Kamber, Christoph T., Speer, Oliver, Franzoso, Francesca D., Schmugge, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7799768/ https://www.ncbi.nlm.nih.gov/pubmed/33428668 http://dx.doi.org/10.1371/journal.pone.0244848 |
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