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Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids

Glioblastoma (GBM) is the most aggressive brain cancer and its relapse after surgery, chemo and radiotherapy appears to be led by GBM stem cells (GSCs). Also, tumor networking and intercellular communication play a major role in driving GBM therapy-resistance. Tunneling Nanotubes (TNTs), thin membra...

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Detalles Bibliográficos
Autores principales: Pinto, Giulia, Saenz-de-Santa-Maria, Inés, Chastagner, Patricia, Perthame, Emeline, Delmas, Caroline, Toulas, Christine, Moyal-Jonathan-Cohen, Elizabeth, Brou, Christel, Zurzolo, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7800365/
https://www.ncbi.nlm.nih.gov/pubmed/33245115
http://dx.doi.org/10.1042/BCJ20200710