Stimulation of Sigma-1 Receptor Protects against Cardiac Fibrosis by Alleviating IRE1 Pathway and Autophagy Impairment

Sigma-1 receptor (Sig1R), a chaperone in the endoplasmic reticulum (ER) membrane, has been implicated in cardiac hypertrophy; however, its role in cardiac fibroblast activation has not been established. This study investigated the possible association between Sig1R and this activation by subjecting...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Jing, Li, Miaoling, Li, Dongxu, Xin, Yanguo, Li, Junli, Lei, Song, Wu, Wenchao, Liu, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801073/
https://www.ncbi.nlm.nih.gov/pubmed/33488945
http://dx.doi.org/10.1155/2021/8836818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801073/
https://www.ncbi.nlm.nih.gov/pubmed/33488945
http://dx.doi.org/10.1155/2021/8836818

Ejemplares similares