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Stimulation of Sigma-1 Receptor Protects against Cardiac Fibrosis by Alleviating IRE1 Pathway and Autophagy Impairment

Sigma-1 receptor (Sig1R), a chaperone in the endoplasmic reticulum (ER) membrane, has been implicated in cardiac hypertrophy; however, its role in cardiac fibroblast activation has not been established. This study investigated the possible association between Sig1R and this activation by subjecting...

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Detalles Bibliográficos
Autores principales:	Qu, Jing, Li, Miaoling, Li, Dongxu, Xin, Yanguo, Li, Junli, Lei, Song, Wu, Wenchao, Liu, Xiaojing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801073/ https://www.ncbi.nlm.nih.gov/pubmed/33488945 http://dx.doi.org/10.1155/2021/8836818

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