Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells

A cytoskeletal protein keratin 19 (K19) is highly expressed in breast cancer but its effects on breast cancer cell mechanics are unclear. In MCF7 cells where K19 expression is ablated,we found that K19 is required to maintain rounded epithelial-like shape and tight cell-cell adhesion. A loss of K19...

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Detalles Bibliográficos
Autores principales: Alsharif, Sarah, Sharma, Pooja, Bursch, Karina, Milliken, Rachel, Lam, Van, Fallatah, Arwa, Phan, Thuc, Collins, Meagan, Dohlman, Priya, Tiufekchiev, Sarah, Nehmetallah, Georges, Raub, Christopher B., Chung, Byung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801129/
https://www.ncbi.nlm.nih.gov/pubmed/33393839
http://dx.doi.org/10.1080/19336918.2020.1868694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801129/
https://www.ncbi.nlm.nih.gov/pubmed/33393839
http://dx.doi.org/10.1080/19336918.2020.1868694

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