Plasma deoxyuridine as a surrogate marker for toxicity and early clinical response in patients with metastatic colorectal cancer after 5-FU-based therapy in combination with arfolitixorin

PURPOSE: The aim was to explore the correlation between increasing doses of [6R]-5,10-methylenetetrahydrofolate (arfolitixorin) and plasma concentrations of deoxyuridine (dUr) in patients with metastatic colorectal cancer (mCRC), subjected to 5-fluorouracil (5-FU)-based chemotherapy. The aim was fur...

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Detalles Bibliográficos
Autores principales: Taflin, Helena, Odin, Elisabeth, Carlsson, Göran, Tell, Roger, Gustavsson, Bengt, Wettergren, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801297/
https://www.ncbi.nlm.nih.gov/pubmed/33099678
http://dx.doi.org/10.1007/s00280-020-04173-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801297/
https://www.ncbi.nlm.nih.gov/pubmed/33099678
http://dx.doi.org/10.1007/s00280-020-04173-2

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