Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy

BACKGROUND: Melanoma in-transit metastases (ITMs) are a challenge to treat and associated with systemic disease and poor prognosis. Topical diphencyprone (DPCP), a potent contact sensitizer, is an established treatment for melanoma ITMs. This exploratory study investigated the utility of BRAF mutati...

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Detalles Bibliográficos
Autores principales: Haywood, Sophia, Garioch, Jennifer, Ramaiya, Arjun, Moncrieff, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Melanoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801318/
https://www.ncbi.nlm.nih.gov/pubmed/32542563
http://dx.doi.org/10.1245/s10434-020-08713-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801318/
https://www.ncbi.nlm.nih.gov/pubmed/32542563
http://dx.doi.org/10.1245/s10434-020-08713-1

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