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Preoperative detection of KRAS mutated circulating tumor DNA is an independent risk factor for recurrence in colorectal cancer

Preoperative ctDNA status in relation to recurrence in cases of CRC remains unclear. We examined preoperative ctDNA detection by targeting KRAS gene mutations as a predictive marker for recurrence after CRC surgery. We measured the preoperative KRAS mutated ctDNA status and analyzed the correlation...

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Detalles Bibliográficos
Autores principales: Nakamura, Yuki, Yokoyama, Shozo, Matsuda, Kenji, Tamura, Koichi, Mitani, Yasuyuki, Iwamoto, Hiromitsu, Mizumoto, Yuki, Murakami, Daisuke, Kitahata, Yuji, Yamaue, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801374/
https://www.ncbi.nlm.nih.gov/pubmed/33432066
http://dx.doi.org/10.1038/s41598-020-79909-4